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Image of an immediate family gathering with their extended family members looking at a laptop computer Image of an immediate family gathering with their extended family members looking at a laptop computer
A family living with CGD Montrail, lives with CGD and brother of Markeyah Lakisha,
X-linked carrier and mother of Markeyah Blaze, does not have CGD Eric, father of Brodie and Blaze Markeyah, X-linked carrier and mother of Brodie and Blaze Brodie, born with CGD
A family living with CGD.

Genetics of CGD

Chronic granulomatous disease (CGD) is not contagious. It’s a genetic condition that is passed down through generations of family members.

When someone in your family has been diagnosed with CGD, it’s important to understand how this can impact your family’s health. Research, family conversations, and eventually testing can help uncover more information about who else could be affected by CGD.

Inheritance patterns of CGD

Select each to learn more:

  • X-linked
  • Autosomal recessive

How X-linked CGD could affect your immediate family

Illustration of how X-linked CGD can affect immediate family

How X-linked CGD could affect your extended family

Illustration of how X-linked CGD can affect extended family

Autosomal recessive CGD can affect both males and females. Here is how autosomal recessive CGD could affect your immediate family

Illustration of how autosomal recessive CGD can affect immediate family

How autosomal recessive CGD could affect your extended family

Illustration of how autosomal recessive CGD can affect extended family
  • X-linked

    How X-linked CGD could affect your  immediate family

    Illustration of how X-linked CGD can affect immediate family

    How X-linked CGD could affect your extended family

    Illustration of how X-linked CGD can affect extended family
  • Autosomal recessive

    Autosomal recessive CGD can affect both males and females. Here is how autosomal recessive CGD could affect your immediate family

    Illustration of how autosomal recessive CGD can affect immediate family

    How autosomal recessive CGD could affect your extended family

    Illustration of how autosomal recessive CGD can affect extended family

Who is at risk for CGD?

If one person in the family is diagnosed, it’s likely others have CGD. The mapping of your family tree may help identify family members who should get tested.

Testing immediate and extended family can help find out who:

  • Icon of checkmark May have CGD
  • Icon of clockHas not been diagnosed yet
  • Shuffle iconMay have been misdiagnosed with another condition

Testing and receiving a correct diagnosis may help with potential treatment, future planning, and avoiding serious* infections.

*An infection is serious if you have to go to the hospital and/or get intravenous (IV) antibiotics.